Additional Funding to Develop a Drug for Alzheimer’s Disease

Additional Funding to Develop a Drug for Alzheimer’s Disease

E-Scape Bio announced an extension of its Series A funding to a total of $63 million. Created as a spin-off from research conducted at the Gladstone Institutes, E-Scape Bio is a biopharmaceutical company with a mission to develop new therapies to…

Proteins Linked to HIV Transmission Could Actually Be Beneficial for Reproduction

Proteins Linked to HIV Transmission Could Actually Be Beneficial for Reproduction

Protein fragments found in semen, and previously only known for their ability to enhance HIV infection, also appear to play an important role in reproductive biology. A team of researchers from the Gladstone Institutes, the University of California, San Francisco…

Deepak Srivastava to Lead the International Society for Stem Cell Research Beginning in 2019

Deepak Srivastava to Lead the International Society for Stem Cell Research Beginning in 2019

Deepak Srivastava, MD, was elected vice president of the International Society for Stem Cell Research (ISSCR), the voice of the global stem cell research community. Srivastava, who pioneered the use of stem cells for heart disease, is director of the…

Study Could Help Explain Link Between Seizures and Psychiatric Disorders

Study Could Help Explain Link Between Seizures and Psychiatric Disorders

In a new study published in Cell Reports, scientists at the Gladstone Institutes identified different types of neurons in a brain region called the reticular thalamus. A better understanding of these cells could eventually help explain how both seizures and…

New Study Helps Solve a Great Mystery in the Organization of Our DNA

New Study Helps Solve a Great Mystery in the Organization of Our DNA

​​​After decades of research aiming to understand how DNA is organized in human cells, scientists at the Gladstone Institutes have shed new light on this mysterious field by discovering how a key protein helps control gene organization. Humans have nearly…

Cancer-Cardiac Connection Illuminates Promising New Drug for Heart Failure

Cancer-Cardiac Connection Illuminates Promising New Drug for Heart Failure

A team of researchers at the Gladstone Institutes uncovered a new strategy to treat heart failure, a leading contributor to mortality and healthcare costs in the United States. Despite widespread use of currently-approved drugs, approximately 40% of patients with heart…

Study Reveals a New Method to Address a Major Barrier to Eradicating HIV

Study Reveals a New Method to Address a Major Barrier to Eradicating HIV

Scientists at the Gladstone Institutes discovered that an enzyme called SMYD2 could be a new therapeutic target for flushing out the HIV that hides in infected individuals. Overcoming this latent virus remains the most significant obstacle to a cure. While…

Discovery Offers New Hope to Repair Spinal Cord Injuries

Discovery Offers New Hope to Repair Spinal Cord Injuries

Scientists at the Gladstone Institutes created a special type of neuron from human stem cells that could potentially repair spinal cord injuries. These cells, called V2a interneurons, transmit signals in the spinal cord to help control movement. When the researchers…

Inflammatory Pathways Link to Obsessive Behaviors in a Common Form of Dementia

Inflammatory Pathways Link to Obsessive Behaviors  in a Common Form of Dementia

Scientists from the Gladstone Institutes identified that mutations in a protein commonly linked to frontotemporal dementia (FTD) result in obsessive-like behaviors. They linked these behaviors to immune pathways, implicating that targeting key components of the immune system could be a…

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