Drug Abuse Potential: A Data Analysis Strategy for Nonclinical Self-Administration Studies, New Webinar Hosted by Xtalks

Drug Abuse Potential: A Data Analysis Strategy for Nonclinical Self-Administration Studies, New Webinar Hosted by Xtalks

Press Release (ePRNews.com) - TORONTO - Nov 02, 2018 - If a drug compound (or its metabolites) crosses the blood-brain barrier, then the FDA requires an Abuse Potential Assessment, which includes GLP self-administration, drug discrimination and physical dependency studies. For some drug classes like stimulants (i.e., amphetamine and cocaine), self-administration studies have been widely characterized in several species with the corresponding data analysis being fairly straightforward.

For other drug classes, however, such as sedatives (i.e., phenobarbital, pentobarbital, midazolam), a greater degree of variability between animals and test sessions exists, along with a relatively low self-administration response. As a result, standard statistical analysis typically used to analyze self-administration studies is either too sensitive or not sensitive enough to support characterization of the biological response for this class of drugs.

This live webinar upcoming on Tuesday, Nov. 20, 2018, at 11 a.m. EST (4 p.m. GMT/UK) will present a holistic data analysis strategy for nonclinical self-administration studies, taking into account patterns of response to provide a greater degree of characterization of the reinforcement properties of a drug. Throughout the webinar, featured speakers will provide sample data of this approach from known drugs of abuse including amphetamine, midazolam, ketamine and diamorphine.

Join featured speakers from Covance Sharon Rowton, Ph.D., Scientific Specialist, and Kelly Ashcroft-Hawley, MMath, Principal Statistician, for an insightful and interactive presentation.

For more information or to register for this event, visit Drug Abuse Potential: A Data Analysis Strategy for Nonclinical Self-Administration Studies.  


Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks, visit http://xtalks.com.

For information about hosting a webinar, visit http://xtalks.com/why-host-a-webinar/.


Nima Rajan
Tel: +1 (416) 977-6555 ext 352
Email: nrajan@xtalks.com

Source : Xtalks
Business Info :

You may also like this  


Or using ePRNews Account

Don't have an account ? Sign Up

Register New Account

Or Signup using Email

Already have an account ? Login

Reset Password

Already have an account ? Login


If you have any concerns regarding this press release, please contact the Author / Media Contact / Business of this press release. ePRNews is not resposible for the accuracy of the news posted and do not endorse, support any product/ services/ business mentioned and hereby disclaims any content contained in this press release.