Press Release (ePRNews.com) - TORONTO - Nov 12, 2018 - Autoimmunity is used to describe almost 80 unique illnesses that include multiple sclerosis, systemic lupus erythematosus, type 1 diabetes, psoriasisĀ and rheumatoid arthritis, and is also increasingly a complication of immuno-oncology therapy. Research tools that allow for the study and characterization of autoimmune biology and development of gene signatures that predict an autoimmunity flare or response to a given therapy will be valuable assets for the research community.
In a live webinar upcoming on Monday, Dec. 3, 2018 at 12 p.m. EST, featured speakers will describe a protocol and application for combining Myriad RBM’s TruCultureĀ® system and NanoStringĀ® nCounterĀ® gene expression profiling to generate proteomic and transcriptional profiles of blood from healthy donors stimulated with a cytokine (TNFĪ±) or pathogen-associated molecule (staphylococcal enterotoxin B, SEB).
The speakers Anne Hwang, Ph.D., Scientist III at Myriad RBMĀ Inc., and Nathan Elliott, Ph.D., Scientist II at NanoString Technologies, will cover:
- Applying the TruCulture blood collection and culture system for immune monitoring
- A protocol for isolating RNA from TruCulture samples for downstream analysis using the NanoString nCounter Autoimmune Profiling gene expression panel
- Data demonstrating the reproducibility of the NanoString platform and a correlation between NanoString transcriptional counts and Myriad RBM’s OptiMAP secreted protein measurements
Combining the TruCulture system with nCounter gene expression profiling enables the study of circulating immune responses using a rapid and easy collection and stimulation culture system followed by subsequent profiling of leukocytes from healthy or diseased cohorts.
For more information or to register for this event, visitĀ Investigating the Human Immune Response with Myriad RBM’s TruCultureĀ® System & NanoStringĀ® nCounterĀ® Autoimmune Profiling Panel.
FOR RESEARCH USE ONLY. Not for use in diagnostic procedures.
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Nima Rajan Source :
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