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Gladstone Institutes

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1650 Owens Street
San Francisco, CA 94158
Phone: (415) 734-2000
Website: http://www.gladstoneinstitutes.org

Gladstone is an administratively and financially independent not for profit organization which has a vibrant partnership with the University of California, San Francisco (UCSF), one of the nation's premier health-sciences institutions.

Gladstone Scientists Funded by NIH to Dive Deep Into ApoE4's Role in Alzheimer's Disease

Gladstone Scientists Funded by NIH to Dive Deep Into ApoE4's Role in Alzheimer's Disease

The story of Alzheimer’s disease is familiar and heartbreaking. As neurons degenerate and die, patients slowly lose their memories, their thinking skills, and ultimately, their ability to perform basic day-to-day tasks. For years, clinical trials investigating potential treatments for Alzheimer’s disease…

Predicting Alzheimer's Disease-Like Memory Loss Before It Strikes

Predicting Alzheimer's Disease-Like Memory Loss Before It Strikes

For a person with Alzheimer’s disease, there’s no turning back the clock. By the time she begins to experience memory loss and other worrisome signs, cognitive decline has already set in. And decades of clinical trials have failed to produce…

New Bay Area Spin-Off Company to Develop Drugs for Multiple Sclerosis and Alzheimer's Disease

New Bay Area Spin-Off Company to Develop Drugs for Multiple Sclerosis and Alzheimer's Disease

​​​​Katerina Akassoglou, Ph.D., senior investigator at Gladstone Institutes, has fundamentally changed the way scientists think of neurological disorders. She made the seminal discovery that blood leaks are toxic to the brain by promoting inflammation and destroying neurons. Her research led the scientific…

Two Possible New Ways to Treat Silent Seizures in Children

Two Possible New Ways to Treat Silent Seizures in Children

As early as 3 months of age, infants with a severe form of epilepsy called Dravet syndrome start having convulsive seizures, during which their arms and legs jerk repeatedly. As they become toddlers, another type of seizure begins to appear.…

New Immunotherapy Targeting Blood-Clotting Protein Protects Multiple Sclerosis and Alzheimer's Disease Models

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier—which keeps large molecules in the blood from entering the brain—becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation.…

Growing Human Brain Cells in the Lab

Growing Human Brain Cells in the Lab

Li Gan, PhD, wants to find treatments to help patients with Alzheimer’s disease. Like most researchers, she’s hit a few major roadblocks. When researchers like Gan find potential new drugs, they must be tested on human cells to confirm they…

Deepak Srivastava Appointed President of Gladstone Institutes

Deepak Srivastava Appointed President of Gladstone Institutes

Deepak Srivastava, MD, has been appointed president of Gladstone Institutes, thus succeeding outgoing President R. Sanders (Sandy) Williams, MD. Srivastava’s term will begin on Jan. 1, 2018. He is currently a senior investigator and director of the Gladstone Institute of…

Additional Funding to Develop a Drug for Alzheimer’s Disease

Additional Funding to Develop a Drug for Alzheimer’s Disease

E-Scape Bio announced an extension of its Series A funding to a total of $63 million. Created as a spin-off from research conducted at the Gladstone Institutes, E-Scape Bio is a biopharmaceutical company with a mission to develop new therapies to…

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